Cystic neuroblastoma in an infant: A case report

  • Jasmine Bajracharya Department of Pediatric Surgery, Nepal Medical College Teaching Hospital
  • Sagar Upadhayay Department of Surgery, Nepal Medical College Teaching Hospital
  • Prabhat Poudel Nepal Medical College Teaching Hospital http://orcid.org/0000-0001-9663-9930
  • Binay Khadka Nepal Medical College Teaching Hospital

Abstract

Neuroblastoma is a neoplasm of the peripheral sympathetic nervous system. Depending upon the primary location of the tumor, it can present as incidental finding, hypertension, abdominal pain, and distention with nonspecific clinical signs. Our patient was four-months-old when he developed excessive crying, increased frequency of micturition, and loose bowel movements. On CT scan, a cystic mass was found in the left suprarenal region and was surgically removed. Immunohistochemistry of the mass confirmed the diagnosis of cystic neuroblastoma. The outcome was good after surgical excision and chemotherapy. Early diagnosis and management of cystic neuroblastoma will result in a good outcome.

References

1. Kalaskar RR, Kalaskar AR. Neuroblastoma in early childhood: A rare case report and review of literature. Contemp Clin Dent [Internet]. 2016 Jul;7(3):401–4.
2. Rich BS, La Quaglia MP. Neuroblastoma [Internet]. Pediatric Surgery. 2012. p. 441–58.
3. Özgül E. Magnetic Resonance Imaging Findings of Bilateral Cystic Neuroblastoma: Case Report of a Very Rare Entity. Cureus [Internet]. 2020 Feb 22;12(2):e7073.
4. London WB, Castleberry RP, Matthay KK, Look AT, Seeger RC, Shimada H, Thorner P, Garrett B, Maris JM, Reynolds CP, Cohn SL. Evidence for an age cut-off greater than 365 days for neuroblastoma risk group stratification in the Children’s Oncology Group (COG) [Internet]. Journal of Clinical Oncology. 2005. p. 8500–8500.
5. Vo KT, Matthay KK, Neuhaus J, London WB, Hero B, Ambros PF, Nakagawara A, Miniati D, Wheeler K, Pearson ADJ, Cohn SL, DuBois SG. Clinical, Biologic, and Prognostic Differences on the Basis of Primary Tumor Site in Neuroblastoma: A Report From the International Neuroblastoma Risk Group Project [Internet]. Journal of Clinical Oncology. 2014. p. 3169–76.
6. Dumba M, Jawad N, McHugh K. Neuroblastoma and nephroblastoma: a radiological review [Internet]. Cancer Imaging. 2015.
7. Curtis MR, Mooney DP, Vaccaro TJ, Williams JC, Cendron M, Shorter NA, Sargent SK. Prenatal ultrasound characterization of the suprarenal mass: distinction between neuroblastoma and subdiaphragmatic extralobar pulmonary sequestration. J Ultrasound Med [Internet]. 1997 Feb;16(2):75–83.
8. Castleberry RP. Neuroblastoma. Eur J Cancer [Internet]. 1997 Aug;33(9):1430–7; discussion 1437–8.
9. Alexander A, Weber B, Lorenzo A, Keays M, El-Ghazaly T, Bägli DJ, Pippi Salle JL, Irwin M, Farhat W. Hydronephrosis in children with abdominal and pelvic neoplasms: outcome and survival analysis of a single center pediatric oncology series. J Urol [Internet]. 2011 Oct;186(4 Suppl):1705–1709.
Published
2022-12-27
How to Cite
BAJRACHARYA, Jasmine et al. Cystic neuroblastoma in an infant: A case report. J Soc Surg Nep, [S.l.], v. 25, n. 2, p. 74-76, dec. 2022. ISSN 2392-4772. Available at: <https://www.jssn.org.np/index.php?journal=jssn&page=article&op=view&path%5B%5D=508>. Date accessed: 03 june 2023.